TB-500 (Thymosin Beta-4) — 5mg Vial | Research Grade | Buy Online USA
TB-500 is a synthetic analogue of Thymosin Beta-4 (Tβ4) — a naturally occurring 43-amino-acid actin-sequestering protein expressed in virtually all mammalian cells. TB-500 represents the conserved actin-binding domain fragment LKKTETQ (residues 17–23) that retains the primary biological activities attributed to full-length Thymosin Beta-4 in published preclinical research.
Each vial contains 5mg of lyophilised TB-500 verified to ≥99% HPLC purity. Batch CoA available for every production lot.
Thymosin Beta-4 Research Background
- Actin dynamics and cell migration — Tβ4 is the primary G-actin sequestering peptide in mammalian cells, regulating free actin monomer availability for cytoskeletal polymerisation.
- Wound healing and angiogenesis — Rodent wound-closure models show accelerated healing, reduced inflammation, and increased vascularisation with exogenous Tβ4/TB-500.
- Tendon and muscle repair — Equine and rodent studies for rotator cuff, tendon-to-bone attachment, and cardiac muscle repair protocols.
- Neurological models — Stroke and TBI models suggest Tβ4 promotes neuronal migration and axonal outgrowth.
TB-500 vs Full-Length Thymosin Beta-4
Researchers searching for thymosin beta 4 for sale, buy thymosin beta-4, or thymosin beta 4 tb-500 should note that TB-500 is the synthetic LKKTETQ fragment analogue rather than the full-length 43-AA protein. Multiple studies confirm the fragment recapitulates wound-healing, angiogenic, and actin-regulatory activities of full-length Thymosin Beta-4, making TB-500 the predominant form in preclinical research.
Specification
| Common name | TB-500 / Thymosin Beta-4 analogue |
| Core fragment sequence | LKKTETQ |
| Format | Lyophilised vial |
| Vial size | 5mg |
| Purity | ≥99% by HPLC |
| Reconstitution | Sterile or bacteriostatic water |
| Storage | −20°C lyophilised; 4°C reconstituted (use within 7 days) |
| CoA | Batch HPLC CoA available |
Popular Research Stacks with Thymosin Beta-4
TB-500 is most commonly studied alongside BPC-157 in tissue repair protocols. The pre-blended BPC-157 + TB-500 blend vial (5mg/5mg) offers both compounds in a single vial. Also available: ARA-290 + BPC-157 + TB-500 triple blend. Full Recovery & Repair catalog.
For research and laboratory use only. Not for human or veterinary consumption. EdgeChems supplies this compound exclusively for licensed preclinical research applications.
